Meta-analysis of continuous outcomes combining individual patient data and aggregate data

Network meta-analysis of (individual patient) time to event data alongside (aggregate) count data

BACKGROUND Network meta-analysis methods extend the standard pair-wise framework to allow simultaneous comparison of multiple interventions in a single statistical model. Despite published work on network meta-analysis mainly focussing on the synthesis of aggregate data, methods have been developed that allow the use of individual patient-level data specifically when outcomes are dichotomous or...

Meta-analysis of individual patient data versus aggregate data from longitudinal clinical trials.

BACKGROUND In clinical trials following individuals over a period of time, the same assessment may be made at a number of time points during the course of the trial. Our review of current practice for handling longitudinal data in Cochrane systematic reviews shows that the most frequently used approach is to ignore the correlation between repeated observations and to conduct separate meta-analy...

Network meta - analysis of ( individual patient ) time to event data 1 alongside ( aggregate ) count data

Comparing the Overall Result and Interaction in Aggregate Data Meta-Analysis and Individual Patient Data Meta-Analysis

The aim of the study was to examine how well aggregate data meta-analyses (ADMAs) and individual patient data meta-analyses (IPDMAs) agree in their overall results and how frequently interactions are detected in IPDMAs and ADMAs.ADMA articles immediately published before the IPDMA and matching the research topic were identified. Agreement in the overall result was achieved if the estimate was i...

Patient Safety Culture: A Meta-analysis of Hospital Data

Background and Objectives: Patient safety (PS) is one of the most important and essential elements of quality in healthcare setting. A systematic review and meta-analysis was performed to assess the status of patient safety culture using the Hospital Survey on Patient Safety Culture (HSOPSC). Methods: In this systematic review and meta-analysis study, data were collected through searching dat...